- Author:
- David Nickerson <david.nickerson@gmail.com>
- Date:
- 2025-08-25 22:04:17+12:00
- Desc:
- Adding flattened model to work on the web simulator and the associated files to build the COMBINE archive.
- Permanent Source URI:
- https://staging.physiomeproject.org/workspace/d5c/rawfile/654d22aca937fbfb98adc11b672b7b404e26a22f/Simulation protocols.txt
Simulation protocols for GLUT_ss_oi.sedml:
1. As $g_i$ changes from 1 to 50 mM, the steady-state values of $v$ shift from negative (indicating transport from intracellular to extracellular) to positive (indicating transport from extracellular to intracellular).
2. As $K_{Ai}$ increases from 149.65 to 500 per fmol, a negative flow rate (from intracellular to extracellular) is observed when $g_i = g_o$, indicating thermodynamically inconsistent parameters.
3. As $\kappa_{r1}$ increases from 0.36 to 100 fmol/s, the v_max doesn't change, while the MM constant changes.
